Re: The strange case of the disappearing gastroprotectors
We agree that the association between acid-suppressing drugs and
community-acquired pneumonia is of great interest. We have repeated our
primary analyses of statin use and risk of pneumonia including use of acid
-suppressing drugs as a covariate, and our results change very little. The
adjusted odds ratio for current statin use and risk of pneumonia is 1.25
(95% confidence interval, 1.01 to 1.55), and for cases requiring
hospitalization, it is 1.61 (95% confidence interval, 1.08 to 2.40).
Competing interests:
Jennifer C Nelson did consulting work for GlaxoSmithKline
Competing interests:
No competing interests
28 June 2009
Sascha Dublin
Assistant Investigator
Michael L. Jackson, Jennifer C. Nelson, Noel S. Weiss, Eric B. Larson and Lisa A. Jackson
Rapid Response:
Re: The strange case of the disappearing gastroprotectors
We agree that the association between acid-suppressing drugs and
community-acquired pneumonia is of great interest. We have repeated our
primary analyses of statin use and risk of pneumonia including use of acid
-suppressing drugs as a covariate, and our results change very little. The
adjusted odds ratio for current statin use and risk of pneumonia is 1.25
(95% confidence interval, 1.01 to 1.55), and for cases requiring
hospitalization, it is 1.61 (95% confidence interval, 1.08 to 2.40).
Competing interests:
Jennifer C Nelson did consulting work for GlaxoSmithKline
Competing interests: No competing interests