Intended for healthcare professionals

Letters Neonatal drug withdrawal

Call for increased pharmacovigilance of gabapentin

BMJ 2017; 359 doi: https://doi.org/10.1136/bmj.j5456 (Published 30 November 2017) Cite this as: BMJ 2017;359:j5456
  1. Alyssa M Peckham, assistant professor,
  2. Kathleen A Fairman, adjunct assistant professor,
  3. David A Sclar, professor and chair
  1. Department of Pharmacy Practice, College of Pharmacy-Glendale, Midwestern University, 19555 N 59th Avenue, Glendale, AZ 85308, USA
  1. apeckh{at}midwestern.edu

Huybrechts and colleagues find increased risk of neonatal drug withdrawal when gabapentin and opioids are co-prescribed.1 We conducted the first large scale assessment of the prevalence and clinical consequences of gabapentin misuse.23 The top 1% of gabapentin users consumed or diverted 19% of total gabapentin supply at mean (median) 11 274 (9534) mg/day; nearly 25% of these users exceeded 12 822 mg/day.2 Additionally, 24% …

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