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You have reported the trial by Agar, M.R. et al. (JAMA Intern. Med. 2017; 177: 34-42; your reference #33), but without drawing any inferences from it. According to the independent German drug evaluation service arznei-telegramm (see source below), it constitutes the largest trial done so far, and suggests that neuroleptics (or at least haloperidol and risperidone) actually aggravate mild or moderate delirium, rather than being helpful, and thus should not be used in these cases. Seems logical to me.
Suzanne, Thanks for your feedback about this image, which was sourced from Getty images. Our editorial policy is to use model release images, which means the subject has granted consent for publication.
Re: Delirium and agitation at the end of life
You have reported the trial by Agar, M.R. et al. (JAMA Intern. Med. 2017; 177: 34-42; your reference #33), but without drawing any inferences from it. According to the independent German drug evaluation service arznei-telegramm (see source below), it constitutes the largest trial done so far, and suggests that neuroleptics (or at least haloperidol and risperidone) actually aggravate mild or moderate delirium, rather than being helpful, and thus should not be used in these cases. Seems logical to me.
Any comments on this?
DELIR IN DER PALLIATIVVERSORGUNG – NEUROLEPTIKA SCHLECHTER ALS PLAZEBO. a-t 2017; 48: 19-21,
URL (accessible to subscribers only): https://www.arznei-telegramm.de/html/htmlcontainer.php3?produktid=019_01...)
Competing interests: No competing interests