Letters
BCG vaccination and TB in children
Authors’ reply to Turner and colleagues
BMJ 2014; 349 doi: https://doi.org/10.1136/bmj.g5441 (Published 10 September 2014) Cite this as: BMJ 2014;349:g5441- I Abubakar, professor of infectious disease epidemiology1,
- S Sridhar, research associate2,
- M Eisenhut, consultant paediatrician3,
- A Roy, senior scientist4,
- R J Harris, statistician4,
- L C Rodrigues, professor of epidemiology5,
- P Mangtani, senior lecturer5,
- I Adetifa, paediatrician and medical epidemiologist6,
- A Lalvani, professor of infectious disease2
- 1Centre for Infectious Disease Epidemiology and MRC Clinical Trials Unit, University College London, London, UK
- 2Tuberculosis Research Centre, Respiratory Infections Section, National Heart and Lung Institute, Imperial College London, London, UK
- 3Luton and Dunstable University Hospital, NHS Foundation Trust, Luton, UK
- 4Centre for Infectious Disease Surveillance and Control, Public Health England, London, UK
- 5London School of Hygiene and Tropical Medicine, London, UK
- 6Medical Research Council, Fajara, Gambia
- i.abubakar{at}ucl.ac.uk
Turner and colleagues do not accept our conclusion that BCG prevents Mycobacterium tuberculosis infection without a valid mechanism and propose an alternative hypothesis for an apparent effect.1 2 We presented the consistent epidemiological finding of a protective effect of BCG against tuberculosis infection rather than speculating on a mechanism of action for this …
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